[5][6][7] Casting calls were held in various cities across the country including Los Angeles, California, Charleston, South Carolina, Louisville, Kentucky, Minneapolis, Minnesota, Pittsburgh, Pennsylvania and Phoenix, Arizona.

This season initially featured no changes to the schedule that was used in the previous edition, with episodes airing on Tuesdays, Wednesdays, and Sunday each week.

[15] The Wednesday episode, which aired at 8 pm Eastern Time, featured the live eviction and subsequent Head of Household competition taking place.

The Sunday episode, which aired at 8 pm Eastern Time, featured the food competition and nomination ceremony, as well as some highlights from the previous days.

The web series aired thirty-minute episodes on weeknights, and allowed fans to call in and express their opinions on the events of the game.

[20] This season also saw the return of the Big Brother: After Dark spin-off series, which aired on Showtime Too nightly from midnight to 3 a.m. Eastern Time.

One bedroom features a black and red color theme, while another was decorated with items promoting peace and love.

Each week, the HouseGuests took part in several compulsory challenges that determined who would win food, luxuries and power in the House.

[28] Unlike other versions of Big Brother, the HouseGuests could discuss the nomination and eviction process open and freely.

The jury members were sequestered in a separate house and was not allowed to watch the show except for segments that included all of the HouseGuests.

The jury members were not shown any Diary Room interviews or any footage that included strategy or details regarding nominations.

[36] Memphis was the winner of the car while the losing team of April, Brian, Jerry, Keesha, Libra, and Ollie was placed on the slop diet for the week.

[41] The following day, Brian formed an alliance with Jerry and attempted to get him to nominate Jessie and Renny for eviction due to their conflict.

[42] On Day 2, Jerry nominated Jessie and Renny for eviction, citing their early conflict as the main reason.

[58] The team of April, Jerry, Keesha, Libra, Memphis, and Renny lost, thus being placed on the slop diet for the week.

[65][66] Following this, Steven attempted to convince Jessie and Michelle to use the Power of Veto and backdoor Libra that week, a plan to which they initially were receptive.

[35] For this competition, HouseGuests split into couples and had to communicate with each other from opposite sides of a wall in an attempt to find matching socks.

[81][82] Following this, Jessie attempted on numerous occasions to convince Keesha to use the Power of Veto and nominate Libra, as he felt the other HouseGuests would evict her.

[95] Libra was the winner of the competition but chose to take the Hawaiian vacation from Michelle, leaving her to wear a red leotard.

[108] Though April and Michelle ended the conflict, Jerry insulted Dan's religious and personal beliefs for weeks afterwards.

[115] Despite Jerry's attempts at convincing Michelle to nominate Dan should he use the Power of Veto, she was reluctant about doing so as she wanted Libra evicted that week.

[35] For this competition, HouseGuests participated in a game of Rock, Paper, Scissors, with these being replaced with Slop, Pig Ears, and Crickets.

[127] Renny, hoping to evict April that week, debated nominating Dan or Memphis as a pawn against her in an attempt to keep Jerry and Ollie from being mad at her.

[133][134] Dan, upset with Renny's decision to not nominate April and Ollie together, later debated using the Power of Veto to save Jerry.

[151] Dan's decision led to much controversy inside and outside of the house when Ollie engaged in numerous arguments with the other HouseGuests.

[35] For this competition, HouseGuests dug through barrels of hay in an attempt to find two Veto medallions; the first to complete this would be the winner.

[169][170] On Day 56, Memphis chose to use the Power of Veto to remove Dan from the block, with Renny being the only eligible HouseGuest to be nominated in his place.

[183] On Day 64, Memphis chose to use the Power of Veto to remove himself from the block, with Keesha being the only eligible HouseGuest to nominate in his place.

[189] Dan then cast the sole vote to evict Jerry from the house, making the Renegade alliance the Final Two.

"[208][209] Big Brother 10 came under fire from critics such as the Parents Television Council for airing the word "fucking" during the Tuesday, August 5 episode of the show.