Hosted by Julie Chen Moonves, the show follows a group of contestants (known as HouseGuests), who live in a house together while being constantly filmed and having no communication with the outside world as they compete to win a grand prize of $750,000.

Big Brother depicts a group of contestants, known as HouseGuests, who live inside a custom-built house outfitted with cameras and microphones recording their every move 24 hours a day.

[4][5] Each week, the HouseGuests compete in competitions in order to win power and safety inside the house.

[11] As a response to racial reckoning in the United States and a lack of diverse representation on television, CBS enacted a policy whereby at least 50% of the cast of its reality shows must be BIPOC starting beginning with the 2021–22 broadcast season.

Christie Valdiserri, a 27-year-old from North Hollywood, California, was originally part of the cast, but tested positive for COVID-19 while in sequester and could not compete.

[16][17] Tiffany Mitchell returned for Big Brother 24 to host a Power of Veto competition; Tiffany and the remaining members of The Cookout alliance (Xavier Prather, Derek Frazier, Azah Awasum, Kyland Young, and Hannah Chaddha) also returned for a segment during the final 4 eviction episode of this season.

[18] Azah Awasum, Alyssa Lopez, Derek Xiao, Kyland Young, Tiffany Mitchell, and Xavier Prather competed on the first season of The Challenge: USA.

Julie announced that for the first time ever, Big Brother would have double evictions in back-to-back weeks and a second HouseGuest would be eliminated that evening.

Through various interviews, the show's producers, Allison Grodner and Rich Meehan, debuted the twists for the season.

[65] Color key: CBS announced that Big Brother had been renewed for a twenty-third season on October 28, 2020, with Chen Moonves confirmed to return as host on the same day.

[67] On January 22, 2021, Robyn Kass announced that Kassting, Inc. would not be providing casting services for the upcoming season.

"[72] Immediately upon entering the house two neon signs hung in the entry way, one reading "BB Beach Club" and the other stating "No Risk, No Reward.

"[73] The living room featured floor-to-ceiling azure and teal tinted glass windows, a handmade shark lamp, and a coffee table built of playing cards.

[77][76] On the second floor, the upstairs lounge was designed on a casino game of poker and had black, white, and gold furniture.

[79] Some viewers accused "The Cookout", an all-black six-person alliance, of making voting decisions solely based on race.

The alliance was formed as a collective in hopes of combatting the trend from past seasons of minorities being evicted early, as well as having one of its members becoming the main series' first-ever black winner.

[82] Julie Chen Moonves disapproved of the criticism on the topic, saying that the alliance "is not [racist]" in her opinion, adding that "it's hard for some people who are not of color to understand the importance of [The Cookout] making it this far".