Big Spring is an unincorporated community and census-designated place in Montgomery County, Missouri, United States.

[3] A post office called Big Spring was established in 1830 and remained in operation until 1906.

[4] The community was named for a big spring near the original town site.

[5] Big Spring is in southern Montgomery County along Missouri Route 19, 8 miles (13 km) south of Interstate 70 at New Florence and the same distance north of Hermann and the Missouri River.

This Montgomery County, Missouri state location article is a stub.