Biomesh

[1] Research into more compatible biomaterials occurred in the proceeding decades, including the search for cellular-based materials extracted from humans and animals.

For example, in 1980, research presented at the first ever World Biomaterials Congress detailed the examined use of dermal collagen of sheep to construct biological mesh for reconstructive surgery.

[1][2][5] An August 2015 literature review published by the Canadian Agency for Drugs and Technologies in Health addressed these drawbacks, concluding that "there remains a lack of sufficient evidence to guide clinical practice regarding the use of biological mesh products... Further rigorously designed RCTs are required to clarify comparative clinical effectiveness and safety of the many available biological mesh products for most surgical indications in which their use has been suggested.

Biologic mesh may be acceptable for this purpose or for placement in open wounds as a staged closure in complex abdominal wall reconstruction.

[6][7][8][9] However, the lack of suitable alternatives has made biologic mesh attractive for contaminated field hernia repair.