Bis(chloroethyl) ether is an organic compound with the formula O(CH2CH2Cl)2.
[3] Bis(chloroethyl) ether is less reactive than the corresponding sulfur mustard S(CH2CH2Cl)2.
[3] In the presence of base, it reacts with catechol to form dibenzo-18-crown-6:[4] Bis(chloroethyl) ether can be used in the synthesis of the cough suppressant fedrilate.
It is combined with benzyl cyanide and two molar equivalents of sodamide in a ring-forming reaction.
When treated with strong base, it gives divinyl ether, an anesthetic:[5] The LD50 is 74 mg/kg (oral, rat).