The Bishop Portier House is a historic residence in Mobile, Alabama, United States.

The house, built c. 1834, is one of Mobile's best surviving examples of a Creole cottage with neoclassical details.

[1] The house is named for Michael Portier, Mobile's first Roman Catholic bishop, who made this his home from 1834, until his death in 1859.

Abram Ryan, poet-priest of the South, occupied the northwest corner room on the second floor from 1870, until 1877.

It is one and one-half stories, with a square plan, and a center hall running from front to rear.