Garner spent over two decades as a nationally syndicated overnight disc jockey, first hosting After Midnite for Premiere Networks and then The Blair Garner Show for Nash FM; in-between, he hosted the morning drive time program America's Morning Show, also for Nash FM.
Over his career, Garner has worked at stations across the country, including Dallas, Washington, D.C., Houston, New York City and Los Angeles.
Country music's top stars, including Garth Brooks, Taylor Swift, Tim McGraw, Blake Shelton, and Reba McEntire have made it a point to appear on Blair's show to promote their projects.
Garner has also interviewed stars outside of Nashville, including Pharrell Williams, Pete Buttigieg, Zendaya, Pete Wentz, Kevin Costner, Gwyneth Paltrow, Lionel Richie, Henry Winkler, Joan Rivers, Kathie Lee Gifford, and WWE and UFC stars such as Stone Cold Steve Austin, John Cena and Brock Lesnar.
As of 2021, Premiere continues to use the name for its overnight country show, hosted by Cody Alan from 2013 to 2021, then Granger Smith from 2022 onward.