[3] Brandel was selected by the Minnesota Vikings with the 203rd overall pick in the sixth round of the 2020 NFL draft.
[5][6] Brandel was waived by the Vikings during final roster cuts on September 5, 2020, and was signed to the practice squad the next day.
[9] On September 25, 2021, Brandel was waived by the Vikings and re-signed to the practice squad.
He started three games at left tackle in place of an injured Christian Darrisaw.
On March 11, 2024, Brandel signed a three-year contract extension with the Vikings.