[1] Bo and his cousin Lucas K. "Luke" Duke (Tom Wopat) live in an unincorporated area of the fictional Hazzard County, in Georgia.

[3][4] As with his cousins Luke and Daisy, Bo's tendency to fall in love easily led the Dukes into trouble a few times, most prominently in the feature-length/two-part story "Carnival of Thrills".

The second episode produced and broadcast, "Daisy's Song", is notable for Bo instead wearing a red shirt for much of the story.

After Bo graduated high school in-and-around 1976[7] he became a stock car driver (though he joined the NASCAR Circuit for most of season 5 with his cousin Luke), and he was typically the one known for taking the General on most of its legendary jumps.

Actors John Schneider and Tom Wopat have admitted that, on occasions that the roles were reversed and Luke drove, they found it much more difficult to climb in and out of the opposite window to which they were accustomed.

Although he was a lifelong bachelor, in the 2000 film, he met a Mexican-American woman named Gabrielle (nicknamed Gabby) in Los Angeles and convinced her to go to Hazzard to be with him.