From March 10, 2005, to August 31, 2006, Schieffer was interim weekday anchor of CBS Evening News, and was one of the primary substitutes for Katie Couric and Scott Pelley.

Following his retirement from Face the Nation, Schieffer has continued to work for CBS as a contributor, making many appearances on air giving political commentary covering the 2016 presidential election.

[6] In university he was a member of the Air Force Reserve Officer Training Corps and the Phi Delta Theta fraternity.

[6] It was at the Star Telegram that he received his first major journalistic recognition when John Kennedy was assassinated in Dallas on November 22, 1963.

In the company of Oswald's mother, Marguerite, and his wife, Marina, he was able to use the phone in the police station to call in dispatches from other Star-Telegram reporters in the building.

[citation needed] Schieffer later joined the Star-Telegram's television station, WBAP-TV in Fort Worth, before taking a job with CBS in 1969.

[11] In the wake of Dan Rather's controversial retirement,[12][13] he was named interim anchor for the weekday CBS Evening News.

[16] Schieffer closed the gap with ABC's World News Tonight when co-anchor Bob Woodruff was injured in late January 2006.

On October 13, 2004, Schieffer was the moderator of the third presidential debate between President George W. Bush and Senator John Kerry in Tempe, Arizona.

[21] Schieffer also moderated the third debate of the presidential candidates in 2012, between President Obama and former Massachusetts Governor Mitt Romney, on October 22, in Boca Raton, Florida.

[23][24] On April 8, 2015, Schieffer announced his intention to retire as host of Face the Nation while speaking at his alma mater, Texas Christian University.

[25][26] On the April 12 broadcast of the program, he announced that John Dickerson, the political director for CBS, would succeed him, beginning in June 2015.

[29] Since leaving the anchor desk at CBS Evening News in 2006, Schieffer has entertained his longstanding interest in songwriting by collaborating with musicians in New York and Washington, D.C. His latest efforts have resulted in four songs with the Washington area band, Honky Tonk Confidential, all of which appear on their CD, Road Kill Stew and Other News (with Special Guest Bob Schieffer).

[37] After fellow CBS newscaster and Texan Dan Rather was switched from the White House beat to hosting the documentary show, CBS Reports, in 1974, the October 13, 1974, edition of the Doonesbury comic strip featured a joking fantasy scene in which Schieffer, his successor, haltingly comments on the transition: "It was the affiliates – they just couldn't take him.

Schieffer had a cameo appearance beside Harrison Ford in the 2010 film, Morning Glory, along with his CBS News colleague Morley Safer as well as MSNBC's Chris Matthews.