From the south, the SP5 (Provincial) highway follows the Polcevera valley north from the town of Campomorone.

From the north, the SP160 highway approaches the pass along the Lemme valley via the towns of Gavi and Voltaggio.

The pass is also accessible by off-road mountain paths and is crossed by the Alta Via dei Monti Liguri, a long-distance trail from Ventimiglia (province of Imperia) to Bolano (province of La Spezia).

[3] The Roman consul Spurius Postumius Albinus Magnus had the Via Postumia built in 148 BC.

[4] During the French Revolutionary Wars the Bocchetta Pass was located in territory belonging to the Republic of Genoa.