Boechera yorkii is a rare species of flowering plant in the mustard family known by the common name Last Chance rockcress.

It is endemic to Inyo County, California, where it is known only from the Last Chance Range in Death Valley National Park.

This is a perennial herb growing from a tough, woody caudex with a basal rosette of narrow linear or lance-shaped leaves coated in branching hairs.

The inflorescence atop the stem produces 8 to 35 flowers which grow outward and then droop.

Although the plant is rare, it is not considered particularly vulnerable to human activity because of its remote location in rugged mountain habitat.