It has a land area of 6,930.05 square kilometres (2,675.71 sq mi) and a 2016 census population of 242,399 inhabitants.

Other major industries of the area include transportation, recycling, woodworking and cabinetmaking.

The Centre-du-Québec region derives great benefit from its central location; major centres such as Montreal and Quebec City are within an hour and a half's drive, while secondary centres such as Sherbrooke and Trois-Rivières are close at hand.

The region borders Mauricie, right across the St. Lawrence River, to the north, Montérégie to the west, Chaudière-Appalaches to the east and Estrie to the south.

The Laviolette Bridge, which connects the region to Trois-Rivières, is located in Bécancour and is the only structure in Quebec located in between Montreal and Quebec City that connects both the north and south shores of the St.