She made six voyages for the British East India Company (EIC) before she was sold in 1807 for breaking up.

Captain Alexander Montgomerie sailed from The Downs on 14 January 1793, bound for Bombay and China.

[2] She was part of a convoy of Indiamen that were bringing General Alured Clarke and his troops for the invasion of the Cape Colony.

However, Sphinx ran into Warren Hastings and both vessels returned to port, Exeter accompanying them.

[2] Bombay Castle was part of a convoy that also included Exeter, Dorsetshire, Coutts, and Neptune, the Botany Bay ships Royal Admiral and Anne, and the whaler Seringapatam.

On the morning of 4 August they encountered French squadron consisting of the frigates Concorde, Médée, and Franchise.

[2] Captain Archibald Hamilton sailed from The Downs on 23 December 1802, bound for Bombay and China.

She was part of a convoy of returning East Indiamen and other vessels, all under the command of Captain Nathaniel Dance.

The Royal Navy was unable to provide an escort and the captains of the EIC's China Fleet debated about setting out for home.

As they were passing through the Straits of Malacca on 14 February, they encountered a French squadron under Rear-Admiral the Comte de Linois, who hoped to seize as many of them as he could.

[8] Dance sent the brig Ganges and three Indiamen, one of them Bombay Castle, to approach the strange vessels and investigate.

On 28 February, the British ships of the line HMS Sceptre and Albion joined the Fleet in the Strait and conducted them safely to St Helena.

[2] On the fleet's safe return, the EIC voted rewards to all the officers and seamen involved in the battle.

No sooner had they sailed than bad weather set in and on 5 February the fleet made for Portland Roads, some 10 leagues away.

As they did so, Earl of Abergavenny struck on the Shambles off the Isle of Portland and then sank in Weymouth Bay with the loss of 263 lives, including her captain, out of 402 people on board.