Brainlab develops software and hardware for radiotherapy and radiosurgery, and the surgical fields of neurosurgery, ENT and craniomaxillofacial, spine surgery, and traumatic interventions.

Their products focus on image-guided surgery and radiosurgery, digital operating room integration technologies, and cloud-based data sharing.

[7] The first Brainlab product was a mouse-controlled, menu-driven surgical planning and navigation software, introduced in 1990 at the University of Vienna and exhibited at the Congress of Neurological Surgeons (CNS) Annual Scientific Meeting in Washington, D.C. in 1992.

[17] In the following years, several Brainlab technologies and products received the Red Dot Design Award, including the Kick navigation system, the Curve technology and the Airo Mobile Intraoperative CT.[18] In March 2019, Smith & Nephew announced the acquisition of the orthopaedic joint reconstruction business unit from Brainlab to advance its efforts in robotic surgery.

[20] On September 14, 2022, Stefan Vilsmeier, CEO and Claus Promberger, VP for R&D, from Brainlab, together with clinical partner Professor Cordula Petersen, MD from the UKE (Universitätsklinikum Hamburg-Eppendorf) in Hamburg, were nominated as one of the three finalists for the Federal President’s Award for Innovation and Technology (Deutscher Zukunftspreis) 2022 for the ExacTrac Dynamic technology,[21] a highly precise radiation treatment for tumors in motion.

[22] The prize has been awarded annually by the German Federal President for over 25 years and honours outstanding technical, engineering, scientific as well as software and algorithm-based achievements within Germany.

Brainlab commissioned the artist Alicja Kwade to design an eight-metre-high sculpture made of steel and bronze for the memorial site.

[34] Featured speakers at the official inauguration ceremony on July 11, 2017, were the Bavarian State Minister Ilse Aigner and German Chancellor, Angela Merkel.

[35] Stefan Vilsmeier, a self-taught computer programmer, is a German entrepreneur, inventor,[36] author, founder, president, and CEO of Brainlab.

In 2009, Brainlab began a partnership with Voyant Health, a Tel Aviv, Israel-based company founded in 2003, active in orthopaedic technology.

The first, in January 2020, was VisionTree Software Inc., a San Diego-based company that develops cloud-based, patient-centric data collection and health management technologies.

[47][48][49] In 2020, Brainlab also founded its subsidiary Snke OS, a company with approximately 150 employees, aiming to create the first digital health technology platform for surgery.

[50][51] In March 2021, Brainlab obtained the German company Mint Medical, which is based in Heidelberg and develops image reading and reporting software for clinical routine and research.

Based in Waldkirch, Germany, the family-owned company is active in the development of intraoperative neuromonitoring technology and related equipment for surgical interventions.

[2] Brainlab develops software technology for planning and navigating surgical procedures, including image enhancement and visualization tools.

These can be customised to meet clinical requirements, use standard interfaces and are compatible with various workflows, treatment systems, and positioning technologies.