The heritage-listed Breakfast Creek Hotel is located near the confluence with the Brisbane River and is known for serving XXXX beer exclusively from wooden barrels.

[1] An important Aboriginal camping ground occupied the Breakfast Creek / Hamilton area until it was broken up by police raids in the 1860s.

[citation needed] One of the white first settlers on the creek was Patrick Leslie who, in 1845, built the still-standing Newstead House.

Brisbane's Cantonese community, who had established businesses in Fortitude Valley and built the Temple of the Holy Triad in 1886, settled in the flats around Breakfast Creek and Eagle Farm.

[4] During dry times in the early colony of Moreton Bay, when water from the Roma Street reservoir was depleted, supplies were carted from Breakfast Creek.