The steady life in prison changes with the arrival of wrongly accused inmate Mak Kin-tin (Adam Pak).

In order to protect his life, Kin-tin takes the suggestion of his cellmate, Ho-ching (Louis Cheung), and they work together to plan a precise escape from prison.

In order to avoid the strict supervision of Warden Tang (Kenny Wong), Ho-ching persuades Big Roller to help them but informing him that his daughter is alive and they work together along with Kin-tin to devise an escape plan utilizing each one of their strengths.

Breakout Brothers was theatrically released on 3 December 2020 in Singapore[3] The film was set to open the same day in Hong Kong, due to cinema closures from 2 December 2020 to 17 February 2021 amid the fourth wave of the COVID-19 pandemic in Hong Kong, the film's release was postponed to 25 February 2021 in the territory.

[5] A sequel to the film, Breakout Brothers 2, was released on 13 January 2022 in Macau and Singapore, and on 28 April 2022 in Hong Kong.