William Schmidt, SJ who wanted to open a Catholic secondary school to prepare city boys from Indianapolis for college.

Schmidt, SJ chose the land, supervised the construction, and remained on hand for six years after the school opened to see it was run properly.

In 2019, Charles C. Thompson, the Archbishop of Indianapolis, stated that the school would no longer be entitled to identify as Catholic, because administrators disobeyed him when renewing the contract of a teacher in a same-sex marriage.

[4] On September 23 of the same year, the Jesuits appealed his decision to the Congregation for Catholic Education in Rome, which temporarily rescinded Thompson's order.

[8] Brebeuf Jesuit offers a college-preparatory curriculum for all students, including a wide array of elective, AP, and Honors courses.