Constructionally it formed the 97 km long Uelzen–Langwedel railway, the western section of the America Line.
After the annexation of the Kingdom of Hanover by Prussia and the foundation of the North German Confederation Bremen had a major interest in a shorter railway link to Berlin, in order to improve the competitiveness of its ports.
After Prussia had refused to pay a proportion of the costs, Bremen decided to construct the line at its own expense.
Because funding from Bremen's national budget was not immediately available as a result of the cost of the recently completed Weser diversion, the Union Bank in Berlin was engaged and they had the line built at a cost of 2 million talers.
As a result of the division of Germany the railway link from Bremen to Stendal via Uelzen was severed between Bergen an der Dumme and Salzwedel from the end of the Second World War to 1999.