Brian Robert Matusz (/ˈmætəs/ MAT-əs; February 11, 1987 – January 6, 2025) was an American professional baseball pitcher.

He played in Major League Baseball (MLB) for the Baltimore Orioles and the Chicago Cubs from 2009 to 2016.

Matusz, Josh Romanski, and Matt Couch anchored the Toreros starting rotation.

[2] In the summer of 2007, Matusz pitched for the U.S. national collegiate team, going 3–1 with a 1.33 ERA in four starts as the U.S. finished second in the Pan Am Games in Rio de Janeiro.

[3][4] In 2008 with San Diego, Matusz was named the West Coast Conference Pitcher of the Year, was a finalist for the Roger Clemens Award, and was a first-team All-American.

[13] He returned and got six starts and finished with a 1–4 record with an ERA above 7.00 before being demoted to Triple-A Norfolk on June 30 to work on his velocity.

[14] He was later recalled and continued to struggle, posting a 1–7 record and 9.84 ERA before his removal from the starting rotation in September.

[27] In his final MLB season, he allowed 14 runs in 9 innings in 8 games combined with the Orioles and Cubs.

[32] He made one start, allowing 5 hits and 5 earned runs with 3 walks and 2 strikeouts in 3 innings.

[36] Matusz's brother, Chris, played college baseball at Iowa Wesleyan University.

[37] Matusz died in Phoenix on January 6, 2025, at the age of 37, due to an apparent drug overdose.