Duclos began her media career in television in 1986 when she joined ATV-10 after finishing an Applied Science degree at the Footscray Institute of Technology.
Duclos also reviewed movies on Network Ten's national Saturday morning show "Video Hits", and has established a successful career as a host and guest speaker at many business and entertainment functions and has been a regular columnist with the Herald Sun's Sunday Magazine.
After four years of breakfast radio on Triple M, Duclos in 1997 joined drive show, The Grill Team, sharing the microphone with Dermott Brereton and her former Network Ten colleague Eddie McGuire.
Each host (Peter Berner, Brigitte Duclos, James Brayshaw, Matt Parkinson and Mike Fitzpatrick), had a nickname which they use as their on-air moniker, although they also use their real names.
In 2008, Duclos joined Mix 1011 breakfast show titled Two Women & a Metro alongside Tom Gleeson.