It is approved in the European Union for the debridement (removal of eschar, that is dead and damaged tissue) of severe burn wounds under the brand name Nexobrid.

[1][5] In other contexts, bromelain has been researched for possible anti-inflammatory effects in treating a range of conditions or diseases, but results of these studies are mixed and regarded as preliminary.

These are involved in the breaking down of a number of drugs, including amiodarone, chloroquine, ibuprofen, and warfarin.

[5][10] The medication is extracted from the stem of the pineapple plant (Ananas comosus)[10] by a standardised process, and each lot has to be analysed for its chemical composition.

[5] The gel basis contains water, polyacrylic acid as a gelling agent, and a disodium hydrogen phosphate/sodium hydroxide buffer.