Clostripain (EC 3.4.22.8, clostridiopeptidase B, clostridium histolyticum proteinase B, alpha-clostridipain, clostridiopeptidase, Endoproteinase Arg-C) is a proteinase that cleaves proteins on the carboxyl peptide bond of arginine.
[1][2] It was isolated from Clostridium histolyticum.
The isoelectric point of the enzyme is 4.8-4.9 (at 8 °C), and optimum pH is 7.4~7.8 (against α-benzoyl-arginine ethyl ester).
The composition of the enzyme is indicated to be of two chains of relative molecular mass 45,000 and 12,500.
This hydrolase article is a stub.