Brookline Avenue is a principal urban artery in the city of Boston, Massachusetts.

It runs from Kenmore Square in the Fenway-Kenmore neighborhood, forming a 1.5-mile straight line to its other terminus at Washington Street in the Brookline Village neighborhood of Brookline, Massachusetts.

[1] The Landmark Center, Fenway Park, Emmanuel College, Longwood Medical and Academic Area and Kenmore Square are sites along its length.

[3] It led from the western end of the dam at Sewall's Point (now Kenmore Square) to the Punch Bowl Tavern on Washington Street in Brookline.

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