Bruce is a town situated along the Skuna River in Calhoun County, Mississippi, United States.

According to the United States Census Bureau, Bruce has a total area of 2.4 square miles (6.3 km2), all land.

As of the 2020 United States Census, there were 1,707 people, 714 households, and 335 families residing in the town.

There are three public schools in the district: Bruce, Calhoun City, and Vardaman.

Bruce is a Level 5 High School, which is the highest academic ranking in Mississippi.

Calhoun City is slightly smaller than Bruce High School.

The Bruce Trojan High School baseball team were 2A State Champions in 2012, the Bruce Lady Trojan High basketball team were 2A State Champions in 1998 and 2002, and the Bruce Trojan High School football team were 2A State Champions in 1996.