Brush Creek is an unincorporated community and census-designated place (CDP) in Delaware County, Oklahoma, United States.

It is bordered on the northwest by the city of Jay, the county seat, on the north by Oklahoma State Highway 20, and on the south by Brush Creek, a southwest-flowing tributary of Spavinaw Creek and part of the Neosho River watershed.

According to the United States Census Bureau, the Brush Creek CDP has a total area of 0.83 square miles (2.14 km2), all land.

23.1% of all households were made up of individuals, and 15.4% had someone living alone who was 65 years of age or older.

There were no families and 7.7% of the population living below the poverty line, including no under eighteens and none of those over 64.