Sycamore is a census-designated place (CDP) in Delaware County, Oklahoma, United States.

According to the United States Census Bureau, the Sycamore CDP has a total area of 4.1 square miles (10.7 km2), all land.

The racial makeup of the CDP was 36.61% White, 59.02% Native American, and 4.37% from two or more races.

10.9% of all households were made up of individuals, and 1.8% had someone living alone who was 65 years of age or older.

About 19.6% of families and 8.9% of the population were below the poverty line, including 4.1% of those under the age of eighteen and none of those 65 or over.