Prior to the Great Depression, each West Virginia county had several district school boards.
The city and county students continued to meet in separate buildings until 1958, but all extracurricular activities, such as band and athletics, met together as Buckhannon-Upshur High School.
After World War II, Upshur County's Black population dwindled considerably.
Many Black families left, seeking jobs in northern industrial areas as part of the Great Migration.
The few Upshur County Black students were integrated into the city branch of Buckhannon-Upshur High School without incident.
In 1958, extensive renovations took place at the Upshur, or county, branch of B-UHS, and all high school students began meeting in one facility in grades 10-12.
The Buckhannon, or city, building became Buckhannon-Upshur Junior High School that same year, housing all Upshur County students in grades 7-9.
In 1977, a new campus for Buckhannon-Upshur High School was built two miles south of the old B-UHS on Route 20, and began housing grades 9-12 that year.
The Buckhannon-High that was built in 1909 was condemned in 1977, largely due to its inability to meet modern fire safety standards.
As of the 2009-2010 school year, B-UHS received a PRO-officer through a grant with the Upshur County Sheriff's Department.
This officer assists at the school and goes into the classrooms to talk with students about issues associated with underage drinking, drug use, and other illegal activities.