Following ten years focusing on college preparatory work, college-level instruction was first offered in 1900 culminating in the first baccalaureate degrees in 1905.

Pre-college instruction continued until 1923 when it was discontinued because the high schools in the state had grown enough to adequately perform that task.

The college has since expanded its academic programs, adding graduate degrees in athletic training, business administration, English Writing, and nursing.

The college's athletics teams are the Bobcats, which compete in the NCAA Division II Mountain East Conference, of which it was a founding member in 2013.

Each year, Wesleyan's 21 NCAA II teams successfully[clarification needed] compete at the regional and national levels.

[1][2] Students in the CCE also organized the first collegiate Jump Rope for Heart events in the United States.

The college offers varsity women's sports in basketball, cross country, golf, lacrosse, soccer, softball, swimming, tennis, indoor track and field, outdoor track and field and volleyball.