Founded in 1933 by Isabelle Buckley, the school is located in Sherman Oaks in the San Fernando Valley portion of Los Angeles, California, in the United States.

In 1964, Isabelle Buckley purchased land from the Glenaire Country Club in Sherman Oaks, and by 1973 all five divisions of the school were consolidated at the Stansbury Avenue location.

[4][7] In 2008, the city of Los Angeles approved campus enhancements to be completed over a six-year (non-consecutive) total building period.

[7] By the end of 2016, the school added three new buildings to support academics, including specialized science, technology, engineering, and math (STEM) classrooms, as well as the performing arts, including dance and music rehearsal spaces, a black-box theatre, and a performance and community gathering space.

One Buckley parent, Devin Sloane, plead guilty to paying Singer $250,000 to get his son into the University of Southern California as a water polo recruit.

[4] The campus also houses Cafe Commons, the schools cafeteria, which features fresh, made to order breakfast and lunch, paninis, snacks, drinks, and frozen yogurt.

Buckley's Center for Community and the Arts was completed in 2016 and houses English classrooms and a state-of-the-art theatre for all of the school's productions.

[12] The "Buckley Commitment", which is displayed in all classrooms and is ceremonially signed by students and teachers at the start of each academic year, sets expectations for respect, kindness, honesty, loyalty, self-discipline and self-reliance.

[24] In 2010 and 2012, The Student Voice received "High School Newspaper Silver Crown" awards from the Columbia Scholastic Press Association (CSPA).