From there, the road headed in a general southerly direction, bypassing Wolfenbüttel, Schladen and other, smaller towns.

The southern end of the A 395 came in the town of Vienenburg, at a trumpet interchange with a freeway portion of the B 6/B 6n.

The northernmost 400 m of the A 395, between the junctions Braunschweig-Melverode and Braunschweig-Süd, was not considered to be part of the autobahn system.

There is an at-grade entrance and exit from a large car dealership and gas station along the southbound side of the road just before Braunschweig-Melverode.

Therefore, the A 395 was officially considered to start immediately after that junction, and thus also had no connection to the remaining autobahn network.