She made one voyage as an East Indiaman and then returned to the West Indies trade.

Busiris was offered for sale on 21 April 1815, in the Blackwall Canal,[1] and first appeared in Lloyd's Register (LR) in 1815, with Frankland, master, Redmand & Co., owner, and trade London–Barbados.

On 2 December 1817, Busiris, J. Balston, master, sailed from Britain for Fort William (Calcutta).

Lloyd's Register for 1819, showed Busiris's master changing from Balston to Gardner, and her trade from London–Calcutta to London–St Vincent.

[9] On 30 December, at Cowes, Beaufort in coming in ran across Busiris's hawse, and sustained some damage.