At the end of the 13th century there were three altars in honor of Saints Bartholomew, Innocent and Margaret, in the ancient church of San Salvatore, which had been built by the aristocratic della Croce family which had owned land in the area since 1317.

In 1464, Stefano Della Croce in his will ordered his heirs to build a chapel in honor of the Virgin in the main church of San Salvatore.

In 1664, Giambattista Losetti sold the town to Giuseppe Arconati, to whom the King of Spain conferred the title of Marquess of Busto Garolfo.

[4] In 1461, Aloisio Della Croce, Milanese citizen and owner of numerous lands in the northern sector of the territory of Busto Garolfo, obtained from the town of the village the approval to build in that area a new farmhouse.

Reason of this friendship, is the strong presence in Busto Garolfo of "oriundi" of the Lucanian country, arrived here during the years of the economic boom, with the migrations from the South.