Buttermilk is an unincorporated community in Comanche County, Kansas, United States.

[1] As of 2014, it consisted of a farmhouse and outbuildings, a church and three houses.

The nearby Big Gyp Cave Pictograph Site is on the National Register of Historic Places.

The community is served by Comanche County USD 300 public school district.

This article about a location in Comanche County, Kansas is a stub.