[1] He was ranked a four-star prospect and initially committed to play at the University of Miami before de-committing to evaluate other offers.

[4] In his sophomore year, his first full season as a starter, Henderson recorded 38 tackles, two sacks and two forced fumbles with two interceptions and a team-high seven passes defended and was named second-team All-Southeastern Conference (SEC) by the league's coaches.

[7] Henderson finished his junior season with 33 tackles (three for loss), a sack and 11 passes broken up in nine games and was named first-team All-SEC by the league's coaches and a second-team All-American by the Football Writers Association of America.

[8] Following the end of the Gators' regular season, Henderson announced that he would forgo his final year of eligibility to enter the 2020 NFL draft and also skip Florida's bowl game.

[14][15] In Week 10 against the Green Bay Packers, Henderson forced a fumble on wide receiver Davante Adams which was recovered by teammate Myles Jack during the 24–20 loss.

[17] In October 2020 during a ribbon cutting ceremony, the training center at Christopher Columbus High School, his alma mater, was dedicated in the Henderson Family name due to his generous contribution to the redesign of the facility.