C8 complex

It is part of the membrane attack complex (MAC).

A hereditary deficiency of C8 can result in increased susceptibility to Neisseria infections, such as meningitis and gonorrhea.

C8 is a heterotrimer; it consists of three different subunits.

These are called C8 alpha, beta and gamma chains, encoded by the genes C8A, C8B and C8G respectively.

This article on a gene on human chromosome 9 is a stub.

High Resolution Crystal Structure of Human Complement Component 8 [ 1 ]
Membrane attack complex. Some labels are in Polish.