Governor Kate Brown spoke and the director of the Oregon Health Authority confirmed someone from Washington County who worked at Forest Hills Elementary School in Lake Oswego was being treated at Hillsboro's Kaiser Westside Medical Center.

[4][5] The first case in Multnomah County and fifteenth in Oregon was confirmed on March 10; the patient was treatment at the Veterans Affairs Medical Center.

[6] An employee who worked at the Wells Fargo Center tested positive on March 14, prompting building tenant Davis Wright Tremaine to close offices in Portland.

[15][16] Multnomah County Library closed all branch libraries and Portland Parks and Recreation (PPR) closed arts and community centers, sports facilities, and swimming pools, based on recommendations issued by the Centers for Disease Control and Prevention, Multnomah County Health Department, and the Oregon Health Authority.

The Joint Office of Homeless Services, a collaboration between the City of Portland and Multnomah County, hoped to open additional beds for healthy individuals as overflow from existing shelters.

[32] In late April, Chloe Eudaly and the Portland Bureau of Transportation announced plans to shut down 100 miles of streets to automobile traffic to encourage social distancing for bicyclists and pedestrians.

Six field offices, including one in southeast Portland, continued to operate "by appointment only for limited commercial driver licensing services".

[41] The Oregon Liquor Control Commission (OLCC) permitted stores to operate via curbside pick-up and home delivery temporarily.

[42][43][44] OLCC suspended the enforcement of the Oregon Bottle Bill on March 15 so that grocers can focus on restocking, sanitation and social distancing management.

[48] On March 28, Oregon temporarily lifted the prohibition on self-pump at gas stations to ensure fuel is available during staffing issues related to the pandemic.

[54][62] The Road Runners Club of America's annual convention, slated to be held at the Hilton Portland Hotel during March 19–22, was also canceled.

[64][65][66] While cheer and dance competitions were still being held at the Oregon Convention Center in early March,[67] many events planned to be hosted at the venue were canceled.

[72] On March 23, restrictions prompted the closures of amusement parks, barber shops, bowling alleys, gyms, hair and nail salons, malls, spas, and theaters.

[81] 76 musicians, two conductors, and 19 staff members were laid off, and the organization's president and chief executive officer has submitted an appeal for funding to Governor Brown.

[41] The Liberty Glass, a bar and "neighborhood institution" in north Portland, closed permanently in mid April "due to COVID-19-related financial concerns".

[95] Twelve of 27 laid off Crush Bar employees staged a protest and accused the owner of "[breaking] the law by denying their use of accrued sick hours to cover lost wages".

[96] The strip club Lucky Devil Lounge continued to offer a full menu with home delivery service by "scantily clad strippers" under the business operation Boober Eats.

[97][98] Approximately 25 strippers have participated; dancers are driven and protected by security guards, armed with gloves, masks, and hand sanitizer,[99] and touching by customers is not allowed.

[97] In late April, RingSide Steakhouse sold frozen boxes of steak directly to the general public for the first time in 75 years.

[103] By early May, a few restaurants had confirmed plans to close permanently,[104][105] including Clyde Common[106][107] (which ended up re-opening with outdoor seating and as a market in July).

[108] Later that month, Wong's King and the five restaurants owned by David Machado,[109] including Altabira City Tavern and Nel Centro, confirmed plans to close permanently.

[110][111][112] The respective owners of Bluehour,[113] Irving Street Kitchen, Le Bistro Montage,[114] and Revelry announced plans to close permanently in June.

[132] In April, city officials predicted revenues from lodging taxes would be reduced by 50 percent during the next 12 months, "resulting in a $20 million shortfall".

[135] MLS initially announced a 30-day suspension, when the Timbers were scheduled to play at Providence Park five times between March 12 and mid April.

"[73] Governor Brown and CJ McCollum appeared in a public service announcement to teach children about the disease and how to prevent transmission.

[154][155] On March 26, TriMet temporarily stopped accepting cash payment of fares on buses, asking all riders to pay with the Hop Fastpass system, to minimize the time that boarding passengers spend near the driver.

On March 19, South Metro Area Regional Transit (SMART) buses in Wilsonville began temporarily operating fare-free in support of transit-dependent commuters.

The Port focused on information and pay stations, shuttle buses, and valet booths, following recommendations issued by Multnomah County and the CDC, and made hand sanitizer available for people using ground transportation.

[172] (a requirement that was later imposed nationwide on transit by the Transportation Security Administration)[173] and shortly afterwards equipped all buses and MAX cars with boxes dispensing free face masks.

[187] On March 27, Portland began nightly "solidarity cheers" to recognize health care and other frontline workers, similar to many other cities around the world.