Cairo Regional Airport, (IATA: CIR, ICAO: KCIR, FAA LID: CIR) is a county-owned public-use airport located 4 nautical miles (7.4 km; 4.6 mi) northwest of the central business district of Cairo, Illinois, a city in Alexander County, Illinois, United States.

[1] It is included in the Federal Aviation Administration (FAA) National Plan of Integrated Airport Systems for 2019–2023, in which it is categorized as a local general aviation facility.

Cairo Regional Airport covers an area of 470 acres (190.2 ha) at an elevation of 322 feet (98 m) above mean sea level.

The FBO offers fuel as well as a cafe, a lounge, rest rooms, flight planning stations, and refreshments.

[4][5] For the 12-month period ending September 30, 2020, the airport had 9,000 aircraft operations, an average of 25 per day: 94% general aviation and 6% military.