The California portion of US 95 traverses through the far eastern edges of both Riverside and San Bernardino counties.

The entirety of US 95 in California is designated as Route 95 in the state highway system.

The highway exits I-10 at Intake Boulevard and turns due north, leaving the city limits.

The highway continues north, east of Homer Mountain, to the Nevada state line.

[12] Except where prefixed with a letter, postmiles were measured on the road as it was in 1964, based on the alignment that existed at the time, and do not necessarily reflect current mileage.