The road has remained a state highway after the hospital closed down and the City of Ten Thousand Buddhas monastery was established on the former site in 1976.

Built originally to provide access to the long-defunct Mendocino State Hospital, it is an unsigned spur route off of U.S. Route 101 at Ukiah, ending east at the intersection with East Side Road in Talmage, outside the City of Ten Thousand Buddhas monastery & university (which is located on the grounds of the former Mendocino State Hospital).

West of U.S. Route 101, Talmage Road continues as a city street under Ukiah's control.

[3] Except where prefixed with a letter, postmiles were measured on the road as it was in 1964, based on the alignment that existed at the time, and do not necessarily reflect current mileage.

[1] Segments that remain unconstructed or have been relinquished to local control may be omitted.