The St. Joseph Peninsula extends northward from the west end of Cape San Blas.
It is approximately 10 miles (16 km) south-southwest of the town of Port St. Joe, located at coordinates 29°39′49″N 85°21′20″W / 29.66361°N 85.35556°W / 29.66361; -85.35556.
Cape San Blas was home to a Confederate saltworks where 150 US bushels (5.3 m3) of salt a day were processed by evaporation of seawater.
This halted in 1862, when a landing party from the Union ship, the USS Kingfisher, destroyed the saltworks.
In the aftermath of Hurricane Michael, large swaths of the vacation rentals on the peninsula were heavily damaged.