Carinodrillia quadrilirata is a species of sea snail, a marine gastropod mollusk in the family Pseudomelatomidae, the turrids and allies.

The four lirations on the ribs are rather acute and prominent, and are only on the lower half of the whorls.

The dark white aperture is narrow and measures 3/8 of the total length.

The columella is straight, callous and shows a tubercle at the suture.

[2] This marine species occurs in the Indo-Pacific and off the Philippines and Taiwan.