Caroline of Hesse-Homburg (25 August 1771 – 20 June 1854) was a Princess regent of Schwarzburg-Rudolstadt between 1807 and 1814.

[3] She was the daughter of Frederick V, Landgrave of Hesse-Homburg and his wife, Caroline of Hesse-Darmstadt.

She married in 1791 to Louis Frederick II, Prince of Schwarzburg-Rudolstadt.

She was regent of Schwarzburg-Rudolstadt during the minority of her son Friedrich Günther, Prince of Schwarzburg-Rudolstadt.

Caroline died on 20 June 1854.