It stars Lou Taylor Pucci, Chris Pine, Piper Perabo, and Emily VanCamp as four survivors of a viral pandemic attempting to stay alive amid the looming threat of becoming infected.

Filmed in 2006, it received a limited release in the United States on September 4, 2009, following Pine's breakout performance in Star Trek earlier that year.

Upon arriving, Frank, Brian, Danny, and Kate discover that the serum does not work and the last remaining doctor is preparing to euthanize a group of infected children and himself.

Frank is later forced to bring Jodie to a portable toilet, giving Brian the opportunity to leave them behind and take their vehicle.

As the group runs low on fuel, Brian kills two women to siphon their vehicle, but suffers a gunshot wound.

Additionally, Josh Berry, Tim D. Janis, Dale Malley, and Dylan Kenin portray the survivalists.

[6] Rob Nelson of Variety wrote, "Put into extremely limited release by Paramount Vantage after spending years in studio lockdown, Carriers has moments of genuinely communicable horror and thus deserves better than a de facto theatrical quarantine."