From 1970 the event's distance went from three hours to 250 miles, with Colin Bond driving a Holden LJ Torana GTR XU-1 to victory in 1971 and John Goss winning the last Series Production 500 in 1972 in a Ford XY Falcon GTHO Phase III.

Jim Richards and Tony Longhurst won the first Group A race for driving a BMW 635 CSi, before George Fury scored a pair of victories in turbocharged Nissan Skylines with Glenn Seton in 1986 and Terry Shiel in 1987.

The team of Mark Gibbs and Rohan Onslow driving a Bob Forbes Racing Nissan GT-R had the biggest win of their careers in 1991.

The Holden Racing Team then scored consecutive wins with Craig Lowndes and Greg Murphy, including a memorable duel with Glenn Seton in 1997.

John Bowe, driving with Steve Beards, took his third Sandown 500 win in 2001 in a Ferrari 360, and a Lamborghini Diablo driven by multiple Australian Drivers' Champion Paul Stokell and Anthony Tratt won in 2002.

By 2003, new owners of Queensland Raceway had tired of the relative expense of the 500 kilometre endurance race format, resulting in the Sandown 500 again being contested by V8 Supercars.

From 2013, the event became part of the newly formed Pirtek Enduro Cup within the Supercars season, along with the series' other two-driver races, the Bathurst 1000 and Gold Coast 600.

2015 saw Winterbottom win the Sandown 500 for a second time, having first tasted success in 2006, leading home a Prodrive Racing Australia one-two finish.

The race itself saw Garth Tander, driving with 2012 winner Warren Luff, win his first Sandown 500 in mixed conditions, holding off Shane van Gisbergen by under half a second.

[11] In 2018, Triple Eight Race Engineering dominated the event, scoring a clean sweep of the three podium positions, led by Whincup and Paul Dumbrell who won their third Sandown 500 together.

[2] At the final scheduled running of the event, Triple Eight, who had dropped to two entrants in 2019, were on track for another one-two finish before a mechanical failure while leading took the van Gisbergen/Tander entry, who had started from second last on the grid, out of contention.

Meanwhile, after being relegated to last position on the grid for a technical infringement dating back to the 2019 Bathurst 1000, Scott McLaughlin secured the 2019 Supercars Championship with a round to spare with a ninth place finish driving with Alexandre Prémat.

[14] After three years of a single two-driver endurance race on the calendar, including the return of the Sandown SuperSprint event in 2021 and 2022, the 2023 Supercars Championship re-instated the 500 in its traditional pre-Bathurst slot.

[15] [17] [18] [19] 1 Brodie Kostecki 9 Jack Le Brocq 2 Ryan Wood 25 Chaz Mostert 3 Aaron Love 7 James Courtney 4 Cameron Hill 10 Nick Percat 6 Cam Waters 55 Thomas Randle 8 Andre Heimgartner 14 Bryce Fullwood 12 Jaxon Evans 96 Macauley Jones 11 Anton de Pasquale 17 Will Davison 18 Mark Winterbottom 20 David Reynolds 19 Matthew Payne 26 Richie Stanaway 23 Tim Slade 31 James Golding 87 Will Brown 88 Broc Feeney