The septum pellucidum is a thin, laminated translucent vertical membrane in the midline of the brain separating the anterior horns of the right and left lateral ventricles.

Persistence of the cave of septum pellucidum after infancy has been loosely associated with neural maldevelopment and several mental disorders that correlate with decreased brain tissue.

The septum pellucidum is a thin, triangular, vertical membrane separating the anterior horns of the left and right lateral ventricles of the brain.

Fusion of the CSP is attributed to rapid development of the alvei of the hippocampus, amygdala, septal nuclei, fornix, corpus callosum and other midline structures.

[4] CSP is one of the distinguishing features of individuals displaying symptoms of dementia pugilistica (chronic traumatic encephalopathy).

Noncommunicating cysts can become communicating if they spontaneously rupture, if head trauma occurs, through surgery, or during a diagnostic procedure.