The Cayman Islands competed at the 2015 Pan American Games in Toronto, Ontario, Canada from July 10 to 26, 2015.

The offices of FUSE Marketing Group, in Downtown Toronto served as the location of the house.

[3] The following table lists Cayman Island's delegation per sport and gender.

Originally the country had qualified more athletes including a 4x100 metres relay team.

[6] This will be the first time ever the country has competed in the sport at the Pan American Games.