She won four FAMAS Awards in the films Kulay Dugo ang Gabi, The Passionate Strangers, Lilet and Magnifico.
She also received an award for Best Supporting Actress in the Metro Manila Film Festival for the movie Bulaklak sa City Jail.
Other film credits include Zoom, Zoom Superman (1973), Ang Boyfriend Kong Baduy (1975), Elektrika, Kasi Eh (1976), Star (1979), Katorse (1980), Anak (1981), Angkinin Mo Ako (1983), Ang Boyfriend Kong Kano (1983), Dapat Ka Bang Mahalin (1984), Room 69 (1984) and Bulaklak ng City Jail (1984).
Rodriguez went on an acting hiatus twice, first in the 1960s, when she worked as a fashion model in Europe,[4] and in the 1980s and 1990s, when she resettled in the United States and at one point, took on two jobs simultaneously.
[5] In 1999-2001 she starred in an afternoon drama called May Bukas Pa which aired on RPN 9 and IBC-13 and 2002-2003 played Cherie Gil's mother again in Bituin as Dona Virginia Gaston.