She started her career in an early age, performing at local radio shows when she was six years old.

In 1958 she recorded her first vinyl in São Paulo together with her brother Tony Campello who accompanied her in most of her career.

In 1975 Campello had a brief comeback, presenting with her brother Tony at the Hollywood Rock festival in Rio de Janeiro.

In 1976 she had a cameo appearance at TV Globo telenovela Estúpido Cupido, featuring her music in the soundtrack.

[4] Celly Campello was portrayed by Brazilian actress Marianna Alexandre in the 2022 biographical film Um Broto Legal.