[2] During the period of the 1943–1946 aerial survey, two aircraft and 14 men are recorded to be lost in accidents in the dense tropical rainforest encompassing the Cenepa River.

The water that originates in the Cordillera del Condor establishes a pivotal section of the subsystems that create the Cenepa river basin.

[2] The 1946 United States Army Air Force accomplished the first aerial survey of the Cordillera del Condor zone including the Cenepa River.

[5] The Peruvian Government had a spoken pact of mutual understanding and cooperation with the local communities of the Cenepa River, primarily the Aguaruna People.

[2] As a result of the local communities' ability to produce food resources through small farms like animal breeding; such as chickens and farmland for bananas.

This enabled the army to maintain logistical support through a reliable and steady supply of staples from the locals for their encampments established in isolated locations.

[2] As the Cenepa River along the border is a region of extremely restricted access, traditional dirt roads is the one alternative option other than a helicopter flight.

[citation needed] The Cenepa River Basin has been the subject to territorial disputes between Ecuador and Peru as well as legal conflicts between the local inhabitants and the Peruvian government.

[2] The traditional local communities main influence on the Cenepa River region was the continual rotation of their settlements which provided the basin the opportunity to recover and be maintained.

this establishment contributed to the increasing formation of new population centres and existing communities consisting of relatives that lived traditionally in a widespread manner.

[7] In some regions vegetations is restricted to growing on average fifteen meters; a result of shallow soils over limestone and strong winds.

[2] Flowering and fruiting specimens of Cremastosperma yamayakatense grow up to heights of around 6 to 8 metres in the Cenepa River region in contrast to the Bagua and Condorcanqui provinces where the same species have been recorded having an average of 1.5 meters.

[8] A vast number of frog species have been discovered around the basin, primarily in habitats that consisted of clear and black waters, including some lentic environments.